DIFFERENTIAL RESPONSES TO CARBACHOL, SODIUM NITRO-PRUSSIDE AND 8-BROMO-GUANOSINE 3‘,5’-MONOPHOSPHATE OF CANINE ATRIAL AND VENTRICULAR MUSCLE
نویسندگان
چکیده
منابع مشابه
Effect of 8-bromo-cyclic guanosine monophosphate on intracellular pH and calcium in vascular smooth muscle.
Endothelium-dependent vasodilators, nitrates, and atrial natriuretic factor relax blood vessels by increasing vascular cyclic guanosine monophosphate (cGMP). The mechanisms by which cGMP relaxes vascular smooth muscle (VSM) are not known. Since contraction of VSM is associated with increased intracellular calcium and pH, we hypothesized that cGMP may decrease vascular tone by lowering ionized, ...
متن کاملNote on the Sodium Nitro-prusside Reaction
LEGAL first showed that Weyl's reaction for creatinin was also given by acetone. The reaction consists in the addition of a few drops of a 5 0/0 solution of sodium nitro-prusside, followed by 1 0/0 sodium hydrate. A red colour is produced both with acetone and creatinin solutions. Le Nobel' elaborated the test by showing in the case of acetone that acidifyinog with acetic acid changed the red t...
متن کاملthe differential effects of debate and media analysis as relate to enhancing efl learners critical thinking ability and writing performances
critical thinking ability has an important role in education. accordingly, scholars around the world are searching for new ways for teaching and improving students critical thinking ability. in line with the studies in efl contexts supporting the positive relationship between critical thinking and writing performances, this study investigated the differential effects of halverson’s critical thi...
15 صفحه اولEffect of 8-bromo-cyclic guanosine monophosphate (cGMP) on coronary artery constriction in isolated rabbit hearts.
The vasodilator 8-bromo-guanosine 3':5'-monophosphate (8-bromo-cGMP) effectively counteracts vasopressin-induced coronary artery constriction in a supported perfused working rabbit heart. In this preparation, the coronary arteries remain in contact with the beating heart. The obtuse marginal artery and portions of the left anterior descending coronary artery were deprived of endothelium. Perfus...
متن کاملAtrial natriuretic factor and cyclic guanosine 3',5'-monophosphate in vascular smooth muscle.
To elucidate the molecular mechanism of the vascular action of atrial natriuretic factor (ANF), we investigated the effects of synthetic ANF and sodium nitroprusside on the levels of intracellular cyclic nucleotides and prostacyclin (measured as its stable metabolite 6-keto-prostaglandin F1 alpha) in cultured vascular smooth muscle cells from rat mesenteric artery and, in some experiments, from...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1981
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1981.tb10434.x